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If you have not yet heard of Himalayan Goji, you are not alone. While it has occupied an important place in traditional Asian medicine for countless generations, the secrets of its nutritional benefits have remained a mystery to most of the world. Over the centuries, traditional health practitioners have passed down anecdotal evidence of the power of Goji to each generation. 

From its discovery in the Himalayas, to the present day, those who eat Himalayan Goji Berries—or drink the juice —are awed by its unmatched healing and protective powers. In fact, the people of Central Asia cherish this little berry so much that they devote two weeks every year to festivals in its honor, and from ancient times, medical texts have declared it to be superior for fortifying and maintaining the health of the entire body.

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From Dr. Mindell's Goji: The Himalayan Health Secret
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Usual dosage level: 2 oz. daily
Interleukin-2 (IL-2) is a crucial cytokine (cell protein) that induces potent anti-tumor responses in a variety of cancer models. Several plant polysaccharides have been shown to enhance the production of interleukin-2 (IL-2). Goji LBPs are particularly active in this regard; the enhancing effect of LBP on IL-2 activity was reported by the Institute of Pharmacology and Toxicology in Beijing (1989). In the U.S., IL-2 has been under study as an immune promoting factor since 1983, used for some cancers and for HIV infection.

Other studies from China show that goji berry inhibits the gene mutation induced by TA98 and TA100. Some scientists believe that goji may be a very good supplement to prevent liver cancer because it exerts liver protection and anticancer effects at the same time.

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From Dr. Mindell's Goji: The Himalayan Health Secret
Read more excepts
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Usual dosage level: 4 - 8 oz. daily
In one of the most positive studies yet conducted with goji, 79 advanced cancer patients were treated with the drug LAK/IL-2 combined with goji LBPs in a clinical trail studied by Cao GW et al (1994) at Second Military Medical University in Shanghai, China. 

Their initial results indicated an amazing regression of cancer in patients with malignant melanoma, renal cell carcinoma, colorectal carcinoma, lung cancer, nasopharyngeal carcinoma and malignant hydrothorax. The response rate was an astonishing 40.9 percent for the patients treated with LAK/IL-2 plus goji LBP, while the response rate for patients treated with LAK/IL-2 alone was only 16.1 percent. They also observed that the remission of cancers in patients treated with LAK/IL-2 plus goji lasted significantly longer than those treated without goji.

Their results indicated that goji berry polysaccharides can be used as an adjuvant in cancer therapy.

Another study from China showed LBP increased the sensitivity to radiation therapy and enhanced the immune system for cancer patients.

In one study on a group of cancer patients, the goji berry triggered an increase in both lymphocyte transformation rate and white blood cell count (measures of immune function).

The effect and the mechanism of LBP on inhibiting the growth of human leukemia HL-60 cells were examined. LBP could inhibit the growth of these leukemia cells, and also could induce their death (apoptosis).

Lewis Lung cancer cells were transplanted in C57 BL mice, and the anticancer effects of both goji polysaccharides and radiation were measured. Following the test, it was concluded that goji enhanced the effects of radiation in combating Lewis Lung cancer.

Use of Lycium Barbarum Polysaccharides to Treat Cancer 
Author: G.W. Cao, W.G. Yang, P. Du 
Journal: Chunghua Chung Lui Tsa Chih 16 (Nov. 1994) 
Location: Second Military Medical University, Department of Microbiology, Shanghai, China 
Conclusion: Lycium barbarum polysaccharides can be used as an adjuvant in the treatment of cancer. 
Abstract: Seventy-nine advanced cancer patients were treated with a combination of two immune boosting cytokines (LAK/IL-2*) and Lycium barbarum polysaccharides. Patients treated with only LAK/IL-2 showed a response rate of only 16%, while those treated with both LAK/IL-2 and Lycium barbarum polysaccharides showed a response rate of 40.9%. Moreover, the mean remission in the Lycium barbarum group lasted significantly longer.
*Lymphokine-activated natural killer cells (LAK) and interleukin 2 (IL-2) 

Observation of the Effects of Lycium Barbarum Polysaccharides (LBP) In Combination with LAK/IL-2 Therapy In the Treatment of 75 Cancer Patients
Gau GW, Yang WG, Du P
http://www.richnature.com/products/herbal/articles/lbp-lak.pdf

Effects of Lycium Barbarum and Radiation in Treatment of Lung Cancer 
Author: Lu, C.X., B.Q. Cheng 
Journal: Chung Hsi I Chieh Ho Tsa Chih 11 (Oct 1991) 
Location: Cancer Institute, Ningxia Medical College, Yinchuan, China 
Conclusion: Lycium barbarum enhanced the effects of radiation therapy in the treatment of Lewis Lung cancer. 
Abstract: Lewis Lung cancer cells were transplanted in C57 BL mice, and the anticancer effects of both Lycium barbarum polysaccharides and radiation were measured. Following the test, it was concluded that Lycium barbarum polysaccharides enhanced the effects of radiation in combating Lewis Lung cancer. 

Role of Lycium Barbarum Polysaccharide as an Antioxidant 
Author: X Zhang 
Journal: Chung Kuo Chung Yao Tsa Chih 18 (Feb 1993) 
Location: Beijing Military Hospital, Beijing, China 
Conclusion: The effect of free radical damage on red blood cells can be prevented and reversed by incubation with either Lycium barbarum polysaccharide or superoxidide dismutase. 
Abstract: Researchers incubated cells (Xenopus Oocytes) in a solution containing a free-radical-producing system for 6 hours. The changes in the electrical profile of the cell membranes were measured using a microelectrode electrophysiological technique. The results showed that Lycium barbarum polysaccharide both prevented and reversed free radical damage to cells.

Immune Modulating Effects of Mushroom Extracts, Select Chinese Herbs and Nutrients
Author: Mario Roxas, N.D.
http://www.integrativeinc.com/reviews/Immune%20Modulating%20
Effects%20of%20Mushroom%20Extracts,%20Select%20
Chinese%20Herbs%20and%20Nutrients.pdf

Lycium Fruit
Natural Health, Jan, 1999, by Winnie Yu
http://www.findarticles.com/cf_dls/m0NAH/1_29/54062655/p1/article.jhtml

Lycium Fruit
by Subhuti Dharmananda, Ph.D.
http://www.itmonline.org/arts/lycium.htm

The Wheel of Health
A study of a very healthy people
by G.T. Wrench, M.D. (1938!)
http://journeytoforever.org/farm_library/Wrench_WoH/WoHToC.html

HerbMed® Entry on Lycium
http://www.herbmed.org/viewherb.asp?varHerb_ID=168

The Tibetan Goji Berry:
A delicious-fruit from Central Asia
by Ingrid Naiman
http://www.kitchendoctor.com/foodandrecipes/goji_berries.html

From the same provider, and interesting Lycium Berry Smoothie
http://www.kitchendoctor.com/foodandrecipes/lycium.html

Lycium Fruit. Institute for Traditional Medicine, Portland, Oregon
Dharmananda, S.
http://www.aloe-info.nl/lycium.htm

Quality Chinese Herbs. Lycium Fruit.
Teeguarden, R. 
http://www.qualitychineseherbs.com/herbal_ingredients/lycium_fruit.htm

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